Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunosuppression after cholecystectomy.

M Salo, J Eskola

    Acta Anaesthesiologica Scandinavica
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Cholecystectomy under combined anesthesia temporarily reduces cell-mediated immunity. Lymphocyte counts and responses to mitogens decreased post-surgery but recovered by day three.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nationwide paediatric cohort study of a protective association between allergy and complicated appendicitis.

    The British journal of surgery·2021
    Same author

    Nationwide study of appendicitis in children.

    The British journal of surgery·2019
    Same author

    Clinical findings in relation to mortality in non-tuberculous mycobacterial infections: patients with Mycobacterium avium complex have better survival than patients with other mycobacteria.

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2015
    Same author

    Mug handle affordance and automatic response inhibition: behavioural and electrophysiological evidence.

    Quarterly journal of experimental psychology (2006)·2013
    Same author

    Surveillance of influenza in Finland during the 2009 pandemic, 10 May 2009 to 8 March 2010.

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2011
    Same author

    Foresight in medicine: current challenges with Haemophilus influenzae type b conjugate vaccines.

    Journal of internal medicine·2010

    Area of Science:

    • Immunology
    • Anesthesiology
    • Surgical Science

    Background:

    • Cholecystectomy is a common surgical procedure.
    • The impact of combined anesthesia during cholecystectomy on immune function requires further elucidation.

    Purpose of the Study:

    • To investigate the effects of cholecystectomy under combined anesthesia on various immune parameters.
    • To assess changes in lymphocyte counts and function post-surgery.

    Main Methods:

    • Studied nine patients undergoing cholecystectomy.
    • Analyzed leukocyte and differential counts.
    • Quantified T- and B-lymphocyte populations.
    • Assessed lymphocyte transformation responses to phytohaemagglutinin, concanavalin A, pokeweed mitogen, and purified protein derivative of tuberculoprotein.

    Related Experiment Videos

    Main Results:

    • A decrease in total lymphocyte count was observed post-surgery.
    • No significant change in T-lymphocyte proportion or number.
    • An increase in B-lymphocyte proportion, but no change in surface immunoglobulin markers.
    • A significant reduction in lymphocyte response to all tested mitogens.

    Conclusions:

    • Cholecystectomy under combined anesthesia induces a transient decrease in cell-mediated immunity.
    • Immune function parameters returned to baseline by the third postoperative day.