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Risk factor for steatorrhea in pediatric chronic pancreatitis patients

Lu Hao1,2, Teng Wang2,3, Lin He2

  • 1Department of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Hainan, China.

BMC Gastroenterology
|December 7, 2018
PubMed

Insights

Pediatric chronic pancreatitis (CP) patients with steatorrhea face unique challenges. Key risk factors for steatorrhea in children with CP include early age of onset, diabetes mellitus, and severe acute pancreatitis.

Area of Science:

  • Gastroenterology
  • Pediatric Medicine
  • Pancreatology

Background:

  • Pediatric chronic pancreatitis (CP) presents significant challenges, particularly when accompanied by steatorrhea.
  • Existing research lacks comprehensive data on the natural history of steatorrhea in pediatric CP cases.

Purpose of the Study:

  • To determine the incidence of steatorrhea in pediatric patients with CP.
  • To identify risk factors associated with steatorrhea development in pediatric CP.

Main Methods:

  • A cohort of CP patients (pediatric and adult) was analyzed from January 2000 to December 2013.
  • Steatorrhea rates were calculated, and risk factors were identified for both pediatric (<18 years) and adult groups.

Main Results:

  • Steatorrhea was diagnosed in 15.8% of pediatric CP patients versus 24.0% of adults.
  • In pediatric CP, age at onset, diabetes mellitus (DM), and severe acute pancreatitis (SAP) were significant risk factors for steatorrhea.

Conclusions:

  • Age at onset, DM, and SAP are critical risk factors for steatorrhea in pediatric CP.
  • Close monitoring of high-risk pediatric CP patients is recommended, potentially benefiting from pancreatic exocrine replacement therapy.
Abstract

Keywords:
Chronic pancreatitisPediatricRisk factorsSteatorrhea

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