Related Experiment Video
Updated: Feb 1, 2026
03:56
A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy
Published on: September 13, 2022
2.9K
Flank bulge following subcostal percutaneous nephrolithotomy
Joy Narayan Chakraborty1, Arup Deb2
1Department of Urology, Apollo Hospitals, Guwahati, India, urochakraborty@gmail.com.
Research and Reports in Urology
|December 7, 2018
Summary
This case report details a rare abdominal wall bulge complication after percutaneous nephrolithotomy (PCNL) using a subcostal approach. This finding highlights a potential risk previously unreported for this specific surgical access route.
Area of Science:
- Urology
- Surgical Complications
- Abdominal Wall Anatomy
Background:
- Denervation injury to anterolateral abdominal muscles can cause loss of tone, common after open renal surgery.
- Flank bulge is a rare complication reported after supracostal percutaneous nephrolithotomy (PCNL).
Observation:
- A case of pseudohernia (abdominal wall bulge) occurred after PCNL with subcostal access.
- The patient presented with a painless flank bulge 1 week post-surgery for a partial staghorn calculus.
Findings:
- The abdominal wall bulge persisted for at least 9 months post-PCNL.
- This represents the first reported instance of pseudohernia following PCNL with subcostal access.
Implications:
- Highlights a previously undocumented complication of PCNL with subcostal approach.
- Suggests the need for increased awareness and potential modifications in surgical technique or patient monitoring for subcostal PCNL.
Related Concept Videos
01:06Multipotency and Niche of Bulge Stem Cell
4.2K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
4.2K
02:54Nucleosome Remodeling
11.1K
Nucleosomes are the basic units of chromatin compaction. Each nucleosome consists of the DNA bound tightly around a histone core, which makes the DNA inaccessible to DNA binding proteins such as DNA polymerase and RNA polymerase. Hence, the fundamental problem is to ensure access to DNA when appropriate, despite the compact and protective chromatin structure.
Nucleosome remodeling complex
Eukaryotic cells have specialized enzymes called ATP-dependent nucleosome remodeling enzymes. These enzymes...
Nucleosome remodeling complex
Eukaryotic cells have specialized enzymes called ATP-dependent nucleosome remodeling enzymes. These enzymes...
11.1K
02:45Functional Groups
88.6K
Functional groups are a group of atoms with characteristic properties, which when linked to the carbon skeleton of a molecule, alter the properties of that molecule. For example, the presence of certain functional groups on a molecule will make them hydrophilic, whereas others will make them hydrophobic. These functional groups are an indispensable part of organic chemistry and important components of biological molecules, such as carbohydrates, proteins, lipids, and nucleic acids. Each...
88.6K
02:13Overview of Transposition and Recombination
19.3K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
19.3K
02:30Histone Variants at the Centromere
5.1K
Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
5.1K
02:08Gene Conversion
10.6K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.6K