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Updated: Feb 1, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Hypertrophic obstructive cardiomyopathy and mitral regurgitation in Libman-Sacks endocarditis
Go Yamashita1, Naoki Kanemitsu2, Yasuaki Nakashima3
1Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Goshomachi, Nishikyo-ku, Kyoto, 615-8087, Japan. gogo@kuhp.kyoto-u.ac.jp.
Abstract:
Hypertrophic obstructive cardiomyopathy in Libman-Sacks endocarditis is quite rare and the correct etiological relationship between them is unknown. Some changes may cause a secondary disorganization of the ordinary muscle structure, making a disarray pattern with irregular interwoven myocyte fibers. This case report describes one of the first cases of ventricular septal myectomy and mitral valve replacement for hypertrophic obstructive cardiomyopathy and mitral valve regurgitation associated with Libman-Sacks endocarditis.
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