[The hybrid strategy for complete myocardial revascularization in the frail elderly patient]

Annunziata Nusca1, Rocco A Montone2, Alessandro Sticchi1

  • 1Unità di Scienze Cardiovascolari, Università Campus Bio-Medico, Roma.

Giornale Italiano Di Cardiologia (2006)
|December 7, 2018
PubMed

Insights

Hybrid revascularization offers complete treatment for complex coronary artery disease in frail patients. This tailored approach combines surgical and percutaneous methods, improving outcomes and reducing complications.

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Interventional Cardiology

Background:

  • Multivessel coronary artery disease (CAD) in frail, elderly, multi-morbid patients presents challenges for complete revascularization.
  • Current assessment tools may inadequately capture clinical complexity, leading to incomplete revascularization due to high surgical/procedural risks.

Purpose of the Study:

  • To evaluate the efficacy and safety of a hybrid revascularization strategy in frail patients with multivessel CAD.
  • To determine if this tailored approach improves outcomes compared to standard incomplete revascularization.

Main Methods:

  • Hybrid revascularization strategy combining surgical and percutaneous coronary intervention (PCI).
  • Patient selection focused on individuals with high frailty index and multivessel coronary artery disease.
  • Assessment of clinical outcomes and periprocedural complications.

Main Results:

  • The hybrid strategy facilitates complete myocardial revascularization in this high-risk patient group.
  • Favorable outcomes were observed in frail patients undergoing hybrid revascularization.
  • Lower exposure to periprocedural complications was associated with the hybrid approach.

Conclusions:

  • Hybrid revascularization is a viable and effective strategy for achieving complete revascularization in frail patients with complex multivessel CAD.
  • This tailored approach mitigates risks associated with traditional methods, offering improved results for elderly, multi-morbid individuals.

Related Concept Videos

Hybrid Zones02:29

Hybrid Zones

Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
21.9K
Hybridization of Atomic Orbitals I03:24

Hybridization of Atomic Orbitals I

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
67.3K
Hybridization of Atomic Orbitals II03:35

Hybridization of Atomic Orbitals II

sp3d and sp3d 2 Hybridization
49.0K
Persuasion Strategies01:52

Persuasion Strategies

Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
43.5K
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
10.6K
Coping Strategies: Problem Focused01:27

Coping Strategies: Problem Focused

Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
509