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Plasmacytoid T cells. Immunohistochemical evidence for their monocyte/macrophage origin
F Facchetti1, C de Wolf-Peeters, D Y Mason
1Department of Pathology, Catholic University of Leuven, Belgium.
The American Journal of Pathology
|October 1, 1988
Abstract:
To elucidate the lineage of plasmacytoid T cells, their immunophenotype was studied in reactive lymph nodes with a broad panel of monoclonal antibodies. Plasmacytoid T cells expressed several myelomonocytic markers, and almost all markers highly selective for macrophages. They lacked granulocyte-associated and B or T lymphocyte-associated antigens. These results provide strong evidence that plasmacytoid T cells are of monocyte lineage.