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Pisa syndrome associated with mirtazapine: a case report
Yuji Yamada1, Harumasa Takano2,3, Maki Yamada1
1Department of Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo, 187-8551, Japan.
Background:
Mirtazapine is a noradrenergic and specific serotonergic antidepressant; its pharmacological profile indicates a low risk for dopaminergic adverse effects. To date, there has been only a single case report of Pisa syndrome associated with mirtazapine.
Case Presentation:
The authors report a case involving a 79-year-old woman with bipolar disorder, in whom Pisa syndrome occurred after introduction of mirtazapine, and completely disappeared 3 days after suspension of the drug.
Conclusions:
Aspects of this particular case suggest that Pisa syndrome is a possible side effect of Mirtazapine.
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