Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The intravenous pyelogram in acute pyelonephritis.

K T Kanel1, F J Kroboth, F N Schwentker

  • 1Department of Medicine, University of Pittsburgh School of Medicine, PA 15261.

Archives of Internal Medicine
|October 1, 1988
PubMed
Summary

Uroradiography in acute pyelonephritis rarely changes management in healthy patients. Persistent fever after 72 hours of antibiotics significantly increases the diagnostic yield of genitourinary abnormalities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dysregulation of neurosteroids in obsessive compulsive disorder.

Journal of psychiatric research·2008
Same author

Sex differences in the pharmacokinetics of dehydroepiandrosterone (DHEA) after single- and multiple-dose administration in healthy older adults.

Journal of clinical pharmacology·2000
Same author

Alprazolam increases dehydroepiandrosterone concentrations.

Journal of clinical psychopharmacology·1999
Same author

Correlates and prevalence of benzodiazepine use in community-dwelling elderly.

Journal of general internal medicine·1998
Same author

Delayed severe hypertriglyceridemia from tamoxifen.

The New England journal of medicine·1997
Same author

Alprazolam in young and elderly men: sensitivity and tolerance to psychomotor, sedative and memory effects.

The Journal of pharmacology and experimental therapeutics·1997

Area of Science:

  • Nephrology
  • Urology
  • Infectious Diseases

Background:

  • Acute pyelonephritis often necessitates hospitalization and imaging studies.
  • The utility of routine uroradiography in managing acute pyelonephritis is debated due to low diagnostic yield.

Purpose of the Study:

  • To identify clinical predictors that enhance the specificity of intravenous pyelography in acute pyelonephritis.
  • To determine the impact of uroradiography on patient management in this cohort.

Main Methods:

  • Retrospective cohort study of 67 hospitalized patients with acute pyelonephritis.
  • Analysis of clinical data, fever curves, comorbidities, and pathogen sensitivities.
  • Evaluation of the impact of imaging findings on clinical management decisions.

Related Experiment Videos

Main Results:

  • Only 8% of patients had genitourinary abnormalities influencing management; over 90% of studies did not alter care.
  • Persistent fever (≥72 hours of antibiotics) increased the diagnostic yield of significant abnormalities from 8% to 36%.
  • Diabetes and non-ampicillin-sensitive E. coli infections showed trends toward increased abnormalities, but lacked statistical significance.

Conclusions:

  • Routine uroradiography in acute pyelonephritis has limited utility for management in most otherwise healthy patients.
  • Fever persistence beyond 72 hours of appropriate antibiotic therapy is a key indicator for considering uroradiography.
  • Further investigation is warranted for specific patient subgroups like diabetics or those with resistant pathogens.