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Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
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Optic Nerve Head Drusen: An Update.

Edward Palmer1, Jesse Gale1,2,3, Jonathan G Crowston4

  • 1Surgery & Anaesthesia, University of Otago Wellington, Wellington, New Zealand.

Neuro-Ophthalmology (Aeolus Press)
|December 8, 2018
PubMed
Summary
This summary is machine-generated.

Optic disc drusen, benign calcium deposits, are common and often undetected. New research proposes a refined hypothesis on their cause, supported by advanced imaging and long-term data.

Keywords:
Optic disc drusencalcificationcongenital anomaliesmitophagyneurodegenerationoptic disc oedemapapilloedema

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Optic nerve head drusen are benign, acellular calcium concretions typically forming anterior to the lamina cribrosa.
  • Advanced imaging like optical coherence tomography (OCT) reveals drusen are more common than previously thought, often present in clinically normal optic discs.
  • While drusen can change in early life, they are generally stable in adulthood and may be linked to visual field defects or optic neuropathies.

Purpose of the Study:

  • To propose a refined hypothesis for the etiology of optic disc drusen.
  • To synthesize recent findings from long-term clinical data and OCT imaging.
  • To identify areas for future research into the biomechanical forces involved in drusen formation.

Main Methods:

  • Review of long-term clinical data.
  • Analysis of optical coherence tomography (OCT) imaging.
  • Formulation of a new etiological hypothesis based on integrated data.

Main Results:

  • Optic disc drusen are common, with prevalence potentially underestimated in previous studies.
  • Drusen exhibit characteristic changes in early life and stability in adulthood.
  • Association of drusen with visual field defects and anterior ischemic optic neuropathy is noted.

Conclusions:

  • A refined hypothesis for the cause of optic disc drusen is proposed, integrating clinical and OCT findings.
  • Further studies are needed to elucidate the biomechanical forces driving optic disc drusen formation.
  • Understanding drusen etiology may improve diagnosis and management of associated visual complications.