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The Estimation of Economic Burden of Hepatitis C Virus Infection in Iran
Mehdi Mohammadzadeh1,2, Hamid Derafshi3,4, Tayebeh Ghari2,5
1Dept. of Pharmacoeconomy and Administrative Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Insights
Hepatitis C Virus (HCV) infection significantly impacts liver health and incurs substantial economic costs. This study reveals that HCV
Area of Science:
- Hepatology
- Public Health
- Health Economics
Background:
- Hepatitis C Virus (HCV) infection is a leading cause of liver disease, mortality, and morbidity.
- HCV contributes to chronic liver disease, cirrhosis, and hepatocellular carcinoma.
- This autoimmune liver disease presents a significant economic burden.
Purpose of the Study:
- To estimate the economic and social burden of Hepatitis C Virus (HCV) infection in Iran.
- Quantify direct and indirect costs associated with HCV.
- Assess the impact on disability-adjusted life years (DALYs) and social welfare.
Main Methods:
- A cohort of 200 HCV patients from Tehran, Karaj, and Tabriz, Iran, were enrolled in 2015.
- Direct and indirect costs were calculated to determine the overall economic burden.
- DALYs and social welfare impacts were estimated.
Main Results:
- The total economic burden of HCV infection was estimated at 26,242.8 purchasing power parity (PPP$).
- Intangible costs associated with HCV were calculated to be 207,421.6 PPP$.
- Direct costs per patient exceed average household consumption expenditure.
Conclusions:
- HCV infection imposes a substantial financial strain on patients.
- Implementing policies to control HCV and enhance insurance coverage is recommended.
- Reducing patient costs should be a public health priority.
Background:
One of the major causes of liver-related mortality and morbidity is Hepatitis C Virus (HCV) infection. It is also one of the reasons behinds of chronic liver disease and related complications such as cirrhosis and hepatocellular carcinoma. This autoimmune liver disease imposes a high economic burden on individuals and the society. This study aimed to estimate burden of HCV in Iran.
Methods:
Overall, 200 patients with HCV infection, referred to hospitals in three cities of Tehran, Karaj and Tabriz, Iran during year 2015, were randomly enrolled. To estimate the total burden of hepatitis, direct and indirect costs, costs of DALYs and social welfare were calculated.
Results:
Economic burden of HCV infection was obtained 26242.8 purchasing power parity (PPP$). Intangible costs of HCV was calculated 207421.6 PPP$.
Conclusion:
Total direct costs of HCV for each patient are more than household consumption expenditure. Therefore, it is a reasonable policy to control and increase insurance coverage of HCV patients in order to decrease their costs.
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