The Estimation of Economic Burden of Hepatitis C Virus Infection in Iran

Mehdi Mohammadzadeh1,2, Hamid Derafshi3,4, Tayebeh Ghari2,5

  • 1Dept. of Pharmacoeconomy and Administrative Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Insights

Hepatitis C Virus (HCV) infection significantly impacts liver health and incurs substantial economic costs. This study reveals that HCV

Area of Science:

  • Hepatology
  • Public Health
  • Health Economics

Background:

  • Hepatitis C Virus (HCV) infection is a leading cause of liver disease, mortality, and morbidity.
  • HCV contributes to chronic liver disease, cirrhosis, and hepatocellular carcinoma.
  • This autoimmune liver disease presents a significant economic burden.

Purpose of the Study:

  • To estimate the economic and social burden of Hepatitis C Virus (HCV) infection in Iran.
  • Quantify direct and indirect costs associated with HCV.
  • Assess the impact on disability-adjusted life years (DALYs) and social welfare.

Main Methods:

  • A cohort of 200 HCV patients from Tehran, Karaj, and Tabriz, Iran, were enrolled in 2015.
  • Direct and indirect costs were calculated to determine the overall economic burden.
  • DALYs and social welfare impacts were estimated.

Main Results:

  • The total economic burden of HCV infection was estimated at 26,242.8 purchasing power parity (PPP$).
  • Intangible costs associated with HCV were calculated to be 207,421.6 PPP$.
  • Direct costs per patient exceed average household consumption expenditure.

Conclusions:

  • HCV infection imposes a substantial financial strain on patients.
  • Implementing policies to control HCV and enhance insurance coverage is recommended.
  • Reducing patient costs should be a public health priority.
Abstract

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