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Updated: Feb 1, 2026
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Planarian Immobilization, Partial Irradiation, and Tissue Transplantation
Published on: August 6, 2012
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Accelerated partial breast irradiation: Current status with a focus on clinical practice
Fabiana A Miranda1, Lorine A B Teixeira1,2, Rebeca N Heinzen3
1Department of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil.
The Breast Journal
|December 8, 2018
Summary
Accelerated partial breast irradiation (APBI) is a safe radiation option for early-stage breast cancer, offering reduced treatment volume and time compared to whole breast irradiation (WBI). While local recurrence rates vary, APBI shows comparable survival benefits to WBI.
Area of Science:
- Oncology
- Radiation Oncology
- Breast Cancer Treatment
Background:
- Accelerated partial breast irradiation (APBI) is an emerging radiation technique for select early-stage breast cancer patients.
- APBI targets only the tumor bed, reducing the irradiated breast volume and treatment duration compared to conventional whole breast irradiation (WBI).
Purpose of the Study:
- To review the current clinical practice and status of Accelerated Partial Breast Irradiation (APBI).
Main Methods:
- Review of prospective randomized phase III clinical trials evaluating APBI versus WBI.
- Analysis of outcomes related to local recurrence and survival.
- Focus on clinical practice implications of APBI.
Main Results:
- APBI demonstrates comparable survival outcomes to WBI.
- Clinical trials show variable results regarding local recurrence rates for APBI.
- APBI offers benefits of reduced irradiated breast volume and shorter treatment time.
Conclusions:
- APBI is an acceptable radiation modality for selected early-stage breast cancer patients.
- Further evaluation of APBI techniques and outcomes in clinical practice is warranted.
- APBI provides a valuable alternative to WBI with specific advantages.
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