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Published on: January 27, 2023
A Comparison of Developmental Outcomes of Adolescent Neonatal Intensive Care Unit Survivors Born with a Congenital
Kaitlyn Easson1, Noémi Dahan-Oliel2, Charles Rohlicek3
1Research Institute of the McGill University Health Centre, Montreal, Québec, Canada; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal, Québec, Canada.
Insights
Adolescents with congenital heart defects (CHD) and those born preterm show similar developmental outcomes. Long-term monitoring and support are crucial for both groups to address potential difficulties.
Area of Science:
- Developmental Pediatrics
- Neonatology
- Pediatric Cardiology
Background:
- Congenital heart defects (CHD) and preterm birth are significant perinatal challenges.
- Long-term neurodevelopmental outcomes in these populations require ongoing investigation.
Purpose of the Study:
- To compare cognitive, motor, behavioral, and functional outcomes in adolescents with CHD versus those born preterm.
- To identify similarities and differences in developmental trajectories between these two groups.
Main Methods:
- Cross-sectional study of adolescents (11-19 years) born with CHD (n=80) or preterm (n=128).
- Utilized standardized assessments: Leiter International Performance Scale-Revised (cognitive), Movement Assessment Battery for Children-II (motor), Strengths and Difficulties Questionnaire (behavioral), and Vineland Adaptive Behavior Scale-II (functional).
- Statistical analyses included independent samples t tests and chi-square/Fisher exact tests.
Main Results:
- No significant differences were found in overall cognitive, motor, behavioral, or functional outcomes between adolescents with CHD and preterm adolescents.
- Prevalence of cognitive deficits: 14.3% (CHD) vs. 11.8% (preterm).
- Prevalence of motor difficulties: 43.5% (CHD) vs. 50% (preterm).
- Prevalence of behavioral problems: 23.7% (CHD) vs. 22.9% (preterm).
- Prevalence of functional limitations: 12% (CHD) vs. 7.3% (preterm).
Conclusions:
- Adolescents born with CHD and those born preterm exhibit comparable profiles of developmental deficits.
- Emphasizes the need for sustained, long-term surveillance for both populations.
- Highlights the importance of tailored educational and rehabilitation services to mitigate long-term developmental challenges.
Objective:
To compare cognitive, motor, behavioral, and functional outcomes of adolescents born with a congenital heart defect (CHD) and adolescents born preterm.
Study Design:
Adolescents (11-19 years old) born with a CHD requiring open-heart surgery during infancy (n = 80) or born preterm ≤29 weeks of gestational age (n = 128) between 1991 and 1999 underwent a cross-sectional evaluation of cognitive (Leiter International Performance Scale-Revised), motor (Movement Assessment Battery for Children-II), behavioral (Strengths and Difficulties Questionnaire), and functional (Vineland Adaptive Behavior Scale-II) outcomes. Independent samples t tests and Pearson χ2 or Fisher exact tests were used to compare mean scores and proportions of impairment, respectively, between groups.
Results:
Adolescents born with a CHD and adolescents born preterm had similar cognitive, motor, behavioral, and functional outcomes. Cognitive deficits were detected in 14.3% of adolescents born with a CHD and 11.8% of adolescents born preterm. Motor difficulties were detected in 43.5% of adolescents born with a CHD and 50% of adolescents born preterm. Behavioral problems were found in 23.7% of adolescents in the CHD group and 22.9% in the preterm group. Functional limitations were detected in 12% of adolescents born with a CHD and 7.3% of adolescents born preterm.
Conclusions:
Adolescents born with a CHD or born preterm have similar profiles of developmental deficits. These findings highlight the importance of providing long-term surveillance to both populations and guide the provision of appropriate educational and rehabilitation services to better ameliorate long-term developmental difficulties.
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