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Updated: Feb 1, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive
Yu-Jung Lin1, Fwu-Long Mi2, Po-Yen Lin1
1Department of Chemical Engineering, Institute of Biomedical Engineering, and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan, ROC.
Abstract:
The encapsulation of insulin in micro- or nanodelivery systems may eliminate the need for frequent subcutaneous injections, improving the quality of life of diabetic patients. Formulations for oral, intranasal, pulmonary, subcutaneous, and transdermal administration have been developed. The use of stimuli-responsive polymeric carriers that can release the encapsulated drug in response to changes of the environmental stimuli or external activation enables the design of less invasive or non-invasive systems for smart insulin delivery from depots in the body. This article will look at strategies for the development of responsive delivery systems and the future meeting of the demands of new modes of insulin delivery.
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