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Lithium-induced Thyroiditis in a Patient Having Bipolar Affective Disorder - A Rare Case Report
Praveen Arathil1, Kotchuthressia Mathew1, Dinesh Narayanan1
1Department of Psychiatry, Amrita Institute of Medical Sciences and Research Institute, Kochi, Kerala, India.
Indian Journal of Psychological Medicine
|December 12, 2018
Summary
Lithium therapy for bipolar disorder can cause thyroiditis, a condition affecting thyroid function. This case highlights the importance of monitoring thyroid health in patients on long-term lithium treatment.
Area of Science:
- Endocrinology
- Psychiatry
- Pharmacology
Background:
- Bipolar affective disorder is a chronic mental health condition requiring long-term management.
- Lithium is a first-line mood stabilizer for bipolar disorder, but its use is associated with potential side effects.
- Thyroid dysfunction is a known complication of lithium therapy.
Observation:
- A 22-year-old female with bipolar disorder on lithium presented with manic symptoms.
- Blood tests showed elevated thyroxine and thyroid peroxidase antibodies, with suppressed thyroid-stimulating hormone.
- Technetium thyroid scintigraphy revealed impaired thyroid gland function.
Findings:
- The patient's presentation and laboratory results indicated lithium-induced thyroiditis.
- Elevated thyroid antibodies suggest an autoimmune component to the thyroiditis.
- Reduced thyroid function was confirmed by scintigraphy.
Implications:
- This case underscores the necessity of regular thyroid function monitoring in patients receiving lithium.
- Early detection and management of lithium-induced thyroiditis can prevent further complications.
- Understanding this adverse effect is crucial for optimizing bipolar disorder treatment and patient care.
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