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Temporospatial guidance of activity-dependent gene expression by microRNA: mechanisms and functional implications for

Dylan Kiltschewskij1,2, Murray J Cairns1,2

  • 1School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, 2323, Australia.

Nucleic Acids Research
|December 12, 2018
PubMed

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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