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Updated: Feb 1, 2026

07:05
Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
24.8K
Six years of experience using an advanced algorithm for botulinum toxin application
Gabriela Casabona1, Kai Kaye2, Paula Barreto Marchese3
1Beauty Beyond Skin, Málaga, Brazil.
Journal of Cosmetic Dermatology
|December 12, 2018
Summary
This study presents a customized botulinum toxin (BTX) treatment algorithm for facial rejuvenation, refining injection techniques based on patient-specific factors and outcomes for optimal results.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Cosmetic Surgery
Background:
- Botulinum toxin (BTX) is extensively utilized for facial rejuvenation.
- Key factors influencing BTX treatment efficacy include anatomy, patient demographics, and aging effects.
Purpose of the Study:
- To introduce a systematic algorithm for customizing BTX facial rejuvenation treatments.
- To detail the application of this algorithm in a substantial patient cohort.
Main Methods:
- Pre-treatment digital imaging (relaxed and dynamic facial expressions) informed injection planning.
- OnabotulinumtoxinA (Botox®) was diluted to 100 U/mL and administered using 30-gauge needles and insulin syringes.
- The algorithm guided decisions on injection depth, dosage, and precise anatomical locations.
Main Results:
- The algorithm, refined over 5 years of clinical use, evolved from published guidelines.
- Treatment outcomes led to modifications in injection point number, location, and BTX dosage.
- The individualized approach demonstrated successful facial rejuvenation.
Conclusions:
- Published BTX guidelines serve as a foundational resource for novice practitioners.
- Developing a personalized treatment algorithm is crucial for achieving optimal facial rejuvenation outcomes.
- Individual practitioner experience significantly shapes the refinement of BTX treatment protocols.
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