Jove
Visualize
Contact Us

Related Concept Videos

Conditions on Early Earth02:06

Conditions on Early Earth

100.5K
Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and hydrogen into the primordial atmosphere. However, organisms with the characteristics of life were not initially present on earth. Scientists have used experimentation to determine how organisms evolved that could grow, reproduce, and maintain an internal environment.
100.5K
Biodiversity and Human Values01:24

Biodiversity and Human Values

16.4K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
16.4K
Types of Toxins01:36

Types of Toxins

3.2K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.2K
Effects of Chemicals: Overview01:27

Effects of Chemicals: Overview

2.0K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
2.0K
Bioremediation00:46

Bioremediation

22.1K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
22.1K
What are Biogeochemical Cycles?00:54

What are Biogeochemical Cycles?

39.1K
The most common elements in organic molecules, carbon, hydrogen, oxygen, nitrogen, sulfur, and phosphorus, are only available in the ecosystem in limited amounts. Therefore, these nutrients must be recycled through both biotic and abiotic components of the ecosystem, in processes generally called biogeochemical cycles.
39.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Yield and fidelity of early steps of ribosome-free translation depend on the RNA anchoring.

Nucleic acids research·2026
Same author

ProTides for Antiviral Activity Beyond Liver Cells.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Translation-Promoting Effects of RNA Template Overhangs in the Absence of Ribosomes.

Angewandte Chemie (International ed. in English)·2025
Same author

A quantitative model of enzyme-free copying of RNA with dimers.

Nucleic acids research·2025
Same author

What Makes a Branched Aromatic Compound a Crystallization Chaperone? Insights from a Comparison of Three Organic Scaffolds.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Ribosome-Free Translation up to Pentapeptides via Template Walk on RNA Sequences.

Angewandte Chemie (International ed. in English)·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 19, 2026

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
06:58

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

7.5K

Prebiotic chemistry and human intervention.

Clemens Richert1

  • 1Institute of Organic Chemistry, University of Stuttgart, 70569, Stuttgart, Germany. lehrstuhl-2@oc.uni-stuttgart.de.

Nature Communications
|December 13, 2018
PubMed
Summary
This summary is machine-generated.

Researchers in prebiotic chemistry explore the origins of life from non-living matter. This study reports the frequency of human intervention required to achieve specific experimental outcomes in this field.

More Related Videos

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

10.3K
Conducting Miller-Urey Experiments
11:10

Conducting Miller-Urey Experiments

Published on: January 21, 2014

70.4K

Related Experiment Videos

Last Updated: Jan 19, 2026

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
06:58

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

7.5K
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

10.3K
Conducting Miller-Urey Experiments
11:10

Conducting Miller-Urey Experiments

Published on: January 21, 2014

70.4K

Area of Science:

  • Prebiotic chemistry
  • Origin of life studies
  • Astrobiology

Background:

  • Recreating the conditions for abiogenesis is a key goal in understanding life's origins.
  • Experimental approaches in prebiotic chemistry aim to simulate early Earth environments.
  • Quantifying human influence in these experiments is crucial for reproducibility.

Purpose of the Study:

  • To assess the extent of human intervention in prebiotic chemistry experiments.
  • To provide a metric for the 'naturalness' of simulated abiogenesis pathways.
  • To inform future experimental designs and interpretations in origin of life research.

Main Methods:

  • Systematic review of published prebiotic chemistry studies.
  • Categorization of experimental steps based on the level of human input.
  • Statistical analysis of intervention frequency across different experimental conditions.

Main Results:

  • A significant proportion of reported prebiotic chemistry experiments require substantial human intervention.
  • Intervention levels vary depending on the specific chemical pathways and target molecules being studied.
  • Certain experimental protocols show higher reliance on directed human input for successful outcomes.

Conclusions:

  • The 'naturalness' of simulated prebiotic pathways is often overestimated due to unacknowledged human intervention.
  • Reporting intervention frequency is essential for accurate interpretation of experimental results in origin of life research.
  • Future studies should aim to minimize and transparently report human influence to better understand abiogenesis.