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Hypoxia and hyperbaric oxygen therapy: a review.
1Department of Internal Medicine, Graduate Medical Education, St Vincent Charity Medical Center, Cleveland, OH, USA, Ryan.Choudhury@StVincentCharity.com.
International Journal of General Medicine
|December 13, 2018
Summary
Hypoxia, or low oxygen, affects cells and physiology, often seen in diseases. Hyperbaric oxygen therapy offers a potential treatment for these hypoxic conditions.
Area of Science:
- Physiology
- Molecular Biology
- Cell Biology
Background:
- Hypoxia (low oxygen tension) triggers cellular and physiological responses.
- Prolonged hypoxia is a characteristic of various disease states.
- Molecular biology advances link cellular hypoxia responses to overall physiology.
Purpose of the Study:
- To review the physiological changes associated with hypoxia.
- To discuss cellular responses to hypoxic conditions.
- To explore hyperbaric oxygen therapy for hypoxia-related diseases.
Main Methods:
- Literature review of hypoxia and hyperbaric oxygen therapy.
- Discussion of cellular and physiological impacts of low oxygen.
- Analysis of hyperbaric oxygen therapy as a treatment modality.
Main Results:
- Hypoxia induces a cascade of molecular and cellular activities.
- Cellular responses to hypoxia are increasingly understood through molecular biology.
- Hyperbaric oxygen therapy involves administering 100% oxygen at increased pressures.
Conclusions:
- Understanding cellular responses to hypoxia is crucial for disease management.
- Hyperbaric oxygen therapy is a viable treatment for conditions involving hypoxia and inflammation.
- This review highlights the significance of oxygen therapy in treating hypoxic diseases.
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