Related Experiment Video
Updated: Feb 1, 2026
06:47
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
10.2K
Association Between Atopic Dermatitis and Suicidality: A Systematic Review and Meta-analysis
Jeena K Sandhu1, Kevin K Wu2, Thanh-Lan Bui3
1Currently a medical student at the University of Missouri-Kansas City School of Medicine, Kansas City.
JAMA Dermatology
|December 13, 2018
Summary
Patients with atopic dermatitis (AD) have a significantly increased risk of suicidal ideation and suicide attempts. Dermatologists should screen AD patients for suicidality and refer them for mental health support.
Area of Science:
- Dermatology and Psychiatry
- Epidemiology
- Mental Health Research
Background:
- Atopic dermatitis (AD) is a chronic inflammatory skin condition.
- AD is linked to various psychiatric comorbidities.
- The association between AD and suicidality requires further investigation.
Purpose of the Study:
- To conduct a systematic review and meta-analysis.
- To evaluate the association between atopic dermatitis and suicidality.
- To synthesize existing literature on AD and suicidal behaviors.
Main Methods:
- Systematic search of PubMed, Embase, PsycINFO, and Cochrane databases.
- Inclusion of observational studies evaluating suicidal ideation, attempts, and completed suicide in AD patients.
- Quality assessment using the Newcastle-Ottawa Scale.
Main Results:
- Analysis of 15 studies with over 4.7 million participants.
- Patients with AD showed a 44% increased likelihood of suicidal ideation.
- Patients with AD demonstrated a 36% increased likelihood of suicide attempts compared to controls.
Conclusions:
- Atopic dermatitis is associated with a significantly elevated risk of suicidal ideation and attempts.
- Dermatology providers must be vigilant in screening AD patients for suicidality.
- Prompt mental health referrals are crucial for patients with AD experiencing suicidal thoughts or behaviors.
More Related Videos
Related Concept Videos
01:10Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
01:13Review and Preview
11.3K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.3K
01:20Random and Systematic Errors
14.9K
Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
14.9K
01:09Directing Effect of Substituents: meta-Directing Groups
6.0K
Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.0K
01:17Systematic Sampling Method
13.3K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
Systematic sampling is one of the simplest methods...
Systematic sampling is one of the simplest methods...
13.3K
01:21Association Areas of the Cortex
9.4K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.4K