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Updated: Feb 1, 2026
02:33
Transconjunctival Approach for Injection into the Rat Optic Nerve
Published on: April 4, 2025
901
Optic nerve orbital meningioma.
Summary
Orbital meningiomas often spread from the brain, requiring surgical intervention for vision preservation. Enucleation and exenteration are radical solutions for advanced cases impacting visual acuity.
Area of Science:
- Ophthalmology
- Neurosurgery
- Oncology
Background:
- Orbital meningiomas are tumors that can affect vision.
- Treatment success has improved, with radiotherapy for primary optic nerve sheath meningiomas and surgery for secondary orbital involvement.
- Intracranial tumor propagation necessitates surgical management for orbital meningiomas.
Purpose of the Study:
- To analyze the treatment outcomes of orbital meningioma patients.
- To evaluate the indications for surgical intervention in orbital meningioma cases.
- To assess the role of multidisciplinary collaboration in managing orbital meningiomas.
Main Methods:
- Retrospective analysis of 15 patients with orbital meningioma from 2014-2016.
- Regular dispensary check-ups with yearly magnetic resonance imaging (MRI) of the orbit and brain.
- Histopathological examination for tumor grading.
Main Results:
- 14 out of 15 patients (93.3%) had secondary meningiomas infiltrating the orbit from intracranial origins.
- 3 patients (20%) underwent surgical treatment, including enucleation and partial exenteration.
- Histopathology confirmed meningioma, with 2 cases of Grade I and 1 of Grade II. Surgery was indicated for intracranial tumor infiltration causing vision loss.
Conclusions:
- Multidisciplinary collaboration is crucial for optimal orbital meningioma treatment decisions.
- Ophthalmological examination and imaging are vital for guiding treatment based on visual function changes.
- Radical surgical options like enucleation with partial exenteration may be necessary for advanced orbital infiltration and vision loss.
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