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Preparation of Carbon Nanosheets at Room Temperature

Preparation of Carbon Nanosheets at Room Temperature

Published on: March 8, 2016

Covalent organic nanosheets for bioimaging.

Gobinda Das¹, Farah Benyettou¹, Sudhir Kumar Sharma

¹Chemistry Program , New York University Abu Dhabi (NYUAD) , United Arab Emirates .

Chemical Science

|December 14, 2018

Summary

Triazine-based covalent organic nanosheets (CONs) are water-dispersible and biocompatible. These novel nanomaterials show potential for bio-imaging applications, effectively staining cell nuclei without external agents.

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Preparation of Liquid-exfoliated Transition Metal Dichalcogenide Nanosheets with Controlled Size and Thickness: A State of the Art Protocol

Preparation of Liquid-exfoliated Transition Metal Dichalcogenide Nanosheets with Controlled Size and Thickness: A State of the Art Protocol

Published on: December 20, 2016

Area of Science:

Materials Science
Nanotechnology
Biomedical Engineering

Background:

Covalent organic nanosheets (CONs) possess remarkable physical, chemical, electronic, and optical properties.
Existing applications of CONs are widespread, yet their use in biomedical fields remains limited.
Triazine-based materials are a class of CONs with potential for novel applications.

Purpose of the Study:

To synthesize and characterize nanometer-sized triazine-based CONs.
To evaluate the water dispersibility, stability, and photoluminescence of these CONs.
To assess the biocompatibility, non-toxicity, and potential for cellular imaging of the CONs.

Main Methods:

Exfoliation of bulk triazine-based materials in water to obtain nanosheets.
Characterization of nanosheet properties, including dispersibility, stability, and photoluminescence.
In vitro testing for biocompatibility, cytotoxicity, and cell nucleus staining in HeLa cells.

Main Results:

Nanometer-sized triazine-based nanosheets were successfully obtained via exfoliation.
The nanosheets exhibited excellent dispersibility and stability in water.
Enhanced photoluminescence was observed compared to bulk materials, with successful, agent-free staining of HeLa cell nuclei.

Conclusions:

Triazine-based CONs are biocompatible and non-toxic.
These nanosheets demonstrate promising intrinsic properties for bio-medical applications, particularly in cell imaging.
The ability to stain cell nuclei without external agents highlights their potential as a novel bio-imaging tool.