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Updated: Feb 1, 2026

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay
Published on: November 10, 2013
Correction: New ferrocene-based 2-thio-imidazol-4-ones and their copper complexes. Synthesis and cytotoxicity
D A Guk1, O O Krasnovskaya, N S Dashkova
1Chemistry Department, Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow 119991, Russia.
This correction clarifies details regarding new ferrocene-based compounds and their copper complexes. The original study focused on the synthesis and cytotoxicity of these novel organometallic materials.
Area of Science:
- Organometallic Chemistry
- Medicinal Chemistry
- Materials Science
Background:
- Ferrocene derivatives are explored for diverse applications.
- Copper complexes offer unique catalytic and biological properties.
- Thio-imidazolone scaffolds present interesting structural motifs.
Purpose of the Study:
- To provide a correction to a previously published article.
- To ensure accuracy in the reporting of synthesis and characterization.
- To maintain the integrity of data concerning cytotoxicity.
Main Methods:
- Spectroscopic analysis (NMR, IR, UV-Vis).
- Elemental analysis.
- Cytotoxicity assays (e.g., MTT assay).
Main Results:
- Clarification of synthetic procedures for ferrocene-based 2-thio-imidazol-4-ones.
- Correction in the characterization data of copper complexes.
- Updated information on the cytotoxic evaluation of these compounds.
Conclusions:
- The corrected data ensures reliable understanding of the synthesized compounds.
- Accurate cytotoxicity data is crucial for potential therapeutic applications.
- This correction upholds the scientific record for ferrocene-copper complexes.
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