Related Experiment Video
Updated: Feb 1, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Successful patent ductus arteriosus device closure in a patient with massive pulmonary embolism
Tom Devasia1, Hashir Kareem1, Jwalit Vasantkumar Morakhia1
1Department of Cardiology, Kasturba Medical College & Hospital, Manipal 576104, Karnataka, India.
Insights
Silent patent ductus arteriosus (PDA) can lead to pulmonary embolism, even with a left-to-right shunt. Device closure of large PDA is a viable treatment option, even in patients with massive pulmonary embolism.
Area of Science:
- Cardiology
- Vascular Surgery
Background:
- Patent ductus arteriosus (PDA) is a fetal blood vessel that normally closes after birth.
- PDA can remain open beyond 3 months of age, leading to abnormal left-to-right shunting of blood.
- Silent PDA, undiagnosed in infancy, can present later in life.
Observation:
- A 33-year-old male presented with pulmonary embolism.
- Incidental diagnosis revealed a large PDA with a significant left-to-right shunt.
- Pulmonary embolism is a rare complication of left-to-right shunts.
Findings:
- The patient's pulmonary embolism was successfully managed.
- Elective device closure of the large PDA was performed.
- This case highlights the possibility of PDA in adult pulmonary embolism.
Implications:
- Pulmonary embolism associated with PDA, even large shunts, must be considered in diagnosis.
- Device closure of PDA is a feasible treatment for patients with massive pulmonary embolism.
- Early diagnosis and management of PDA can prevent severe complications like pulmonary embolism.
Abstract:
Patent ductus arteriosus, an essential vasculature structure during fetal life that becomes abnormal after 3 months of age, may be silent. However, the incidence of silent patent ductus arteriosus is as high as 1 in 500 patients. Existence of patent ductus arteriosus leads to left-to-right shunt. The development of pulmonary embolism in left-to-right shunt is rare. We present a case of a 33-year-old male patient who was incidentally diagnosed to have large patent ductus arteriosus along with the left-to-right shunt while being treated for pulmonary embolism. The patient was treated electively with device closure of patent ductus arteriosus. <Learning objective: Pulmonary embolism in left-to-right shunt (although there is a large patent ductus arteriosus) cannot be overlooked. Device closure of large patent ductus arteriosus is possible in patients with massive pulmonary embolism.>.
Related Concept Videos
Pulmonary Embolism I: Introduction
Pulmonary Embolism III: Nursing Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Ecological Succession
Angle Closure Glaucoma: Treatment
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

