Related Experiment Video
Updated: Feb 1, 2026

Microarray Analysis for Saccharomyces cerevisiae
Published on: April 7, 2011
Microarray, IPA and GSEA Analysis in Mice Models
Stephanie N Oprescu1,2, Katharine A Horzmann3, Feng Yue1
1Department of Animal Sciences, Purdue University, West Lafayette, United States.
Abstract:
This protocol details a method to analyze two tissue samples at the transcriptomic level using microarray analysis, ingenuity pathway analysis (IPA) and gene set enrichment analysis (GSEA). Methods such as these provide insight into the mechanisms underlying biological differences across two samples and thus can be applied to interrogate a variety of processes across different tissue samples, conditions, and the like. The full method detailed below can be applied to determine the effects of muscle-specific Notch1 activation in the mdx mouse model and to analyze previously published microarray data of human liposarcoma cell lines.
Related Concept Videos
DNA Microarrays
Mechanistic Models: Compartment Models in Individual and Population Analysis
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
Qualitative Analysis
For instance, group IV...
Dimensional Analysis
Conversion Factors and Dimensional Analysis
The unit...

