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Exercise Training in Cancer Control and Treatment
Jesper Frank Christensen1, Casper Simonsen1, Pernille Hojman1
1Centre of Inflammation and Metabolism (CIM) and Centre for Physical Activity Research (CFAS), Copenhagen University Hospital, Copenhagen, Denmark.
Exercise oncology is a growing field, with evidence showing exercise can prevent cancer, aid treatment, and improve patient well-being. Future research should integrate exercise into standard cancer care for targeted outcomes.
Area of Science:
- Exercise oncology research
- Integrative physiology
- Clinical oncology
Background:
- Exercise is increasingly recognized for its role in cancer prevention, treatment, and survivorship.
- Accumulating evidence supports exercise's benefits for physical functioning and psychosocial outcomes in cancer patients.
Purpose of the Study:
- To present the current state of exercise oncology research.
- To summarize exercise interventions across nearly 700 trials involving over 50,000 cancer patients.
- To discuss the impact of structured exercise programs on cancer-specific, physiological, and psychosocial outcomes.
Main Methods:
- Overview of exercise oncology trials, categorizing interventions by diagnosis, setting, timing, and type.
- Detailed analysis of 292 trials with structured exercise programs.
- Examination of patient challenges and physiological limitations.
Main Results:
- Exercise training is safe and feasible across the cancer continuum.
- Documented benefits include improvements in psychosocial and physiological outcomes.
- Evidence suggests exercise may have direct effects on cancer and its treatment.
Conclusions:
- Exercise training is a well-established supportive care strategy in oncology.
- Future initiatives should focus on integrating exercise into cancer care for targeted, individualized approaches.
- Bridging exercise physiology, clinical oncology, and cancer biology is crucial for advancing the field.
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