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Antioxidant Flavonoids from Asteriscus maritimus.

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    Researchers isolated a new flavonol glycoside, astermaritimoside, and four known flavonoids from Asteriscus maritinus. These compounds demonstrated significant antioxidant activity, particularly in the n-butanol fraction, highlighting their potential therapeutic benefits.

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    Area of Science:

    • Natural Product Chemistry
    • Pharmacognosy
    • Medicinal Plant Research

    Background:

    • Asteriscus maritinus (L.) Less. is a plant species with potential medicinal properties.
    • Flavonoids are a class of plant secondary metabolites known for their diverse biological activities, including antioxidant effects.

    Purpose of the Study:

    • To isolate and characterize chemical constituents from Asteriscus maritinus.
    • To evaluate the antioxidant potential of the isolated compounds and plant extracts.

    Main Methods:

    • Isolation of compounds using chromatographic techniques.
    • Structure elucidation using mass spectrometry and various NMR spectroscopic methods (¹H NMR, ¹³C NMR, COSY, HMQC, HMBC).
    • Antioxidant activity assessment using the electron spin resonance (ESR) method to measure DPPH radical inhibition.

    Main Results:

    • One new flavonol glycoside, astermaritimoside, and four known flavonoids were successfully isolated.
    • The n-butanol fraction of Asteriscus maritinus exhibited remarkable antioxidant activity.
    • The isolated compounds demonstrated good antioxidant properties, correlating with phenolic content.

    Conclusions:

    • Asteriscus maritinus is a source of bioactive flavonoids with significant antioxidant capacity.
    • Astermaritimoside and other isolated flavonoids hold promise for applications requiring antioxidant properties.
    • Further research into the pharmacological effects of these compounds is warranted.