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Related Concept Videos

Appendicitis-I: Introduction01:22

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Related Experiment Video

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High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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Gangrenous appendicitis: No longer complicated.

Andrew B Nordin1, Karen Diefenbach2, Stephen P Sales3

  • 1Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH, 43205; State University of New York University at Buffalo, Department of General Surgery, 100 High St, Buffalo, NY 14203.

Journal of Pediatric Surgery
|December 16, 2018
PubMed
Summary

Treating gangrenous appendicitis as simple appendicitis significantly reduced length of stay and antibiotic use. This approach is safe, showing no increase in postoperative infections or readmissions for appendicitis patients.

Keywords:
Complex appendicitisGangrenous appendicitisPerforation

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Area of Science:

  • Surgical outcomes
  • Infectious disease

Background:

  • Appendicitis severity ranges from inflammation to perforation.
  • Gangrenous appendicitis historically has lower infection rates than perforated cases.

Purpose of the Study:

  • To evaluate treating gangrenous appendicitis as simple appendicitis.
  • To reduce length of stay and antibiotic use without increasing postoperative infections.

Main Methods:

  • Defined complex appendicitis (hole, fecalith, pus, abscess).
  • Switched gangrenous appendicitis to a simple pathway.
  • Reviewed laparoscopic appendectomy patients before and after protocol change.

Main Results:

  • Average length of stay for gangrenous appendicitis decreased from 2.5 to 1.4 days.
  • Antibiotic doses decreased from 5.2 to 1.3.
  • No significant increase in superficial infections or postoperative abscesses.

Conclusions:

  • Gangrenous appendicitis can be safely managed using the simple appendicitis pathway.
  • This approach reduces healthcare resource utilization without compromising patient safety.