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Patterning of Microorganisms and Microparticles through Sequential Capillarity-assisted Assembly
Published on: November 4, 2021
Evaluation of relationships between onychomycosis and vascular diseases using sequential pattern mining.
Chul Hwan Bang1, Jae Woong Yoon2, Hyun Ji Lee1
1Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Onychomycosis (OM) is linked to vascular diseases like peripheral vascular disease and varicose veins. Patients with OM have a higher risk of developing these conditions, highlighting the need for integrated care.
Area of Science:
- Dermatology
- Vascular Medicine
- Biostatistics
Background:
- Onychomycosis (OM) is a prevalent nail condition.
- The association between OM and vascular diseases is debated but significant.
- Sequential pattern mining (SPM) offers a novel approach to analyze dermatological data.
Purpose of the Study:
- To investigate the real-world relationship between OM and vascular diseases using SPM.
- To identify frequent association rules and risk factors in a population-based dataset.
Main Methods:
- Utilized population-based data from 2002-2013.
- Identified OM and vascular disease cases using ICD-10 codes.
- Applied SPM and logistic regression to analyze comorbidity, duration, and 3-year progression risks.
Main Results:
- Patients with varicose veins and peripheral vascular disease showed higher OM comorbidity.
- Shorter diagnostic durations for OM were observed in patients with varicose veins and peripheral vascular disease.
- OM patients faced increased risk for peripheral vascular disease (aOR 1.199) and varicose veins (aOR 1.150).
- Peripheral vascular disease patients had a higher risk of OM (aOR 1.128), but varicose veins did not show a significant risk.
Conclusions:
- A significant association exists between onychomycosis and specific vascular diseases.
- Peripheral vascular disease is a notable risk factor for developing OM.
- Integrated management of OM and vascular comorbidities is crucial for patient care.
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