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Updated: Sep 17, 2026

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy
Published on: May 12, 2020
Evanescent-wave interference lithography enabled by guided-mode-resonance field transfer
Abstract:
We propose a guided-mode-resonance (GMR) approach to evanescent-wave interference lithography that overcomes the severe depth of field and proximity limitations of conventional near-field methods. The scheme consists of a resonant dielectric grating and a photoresist layer separated by a low-index buffer medium, where phase-matched evanescent coupling transfers resonantly enhanced standing-wave fields from the grating to the photoresist. Using rigorous coupled-wave analysis, we design a UV-compatible structure comprising HfO2 grating ridges, a commercial photoresist layer, and a transparent immersion-oil spacer. An example device supports two coupled GMR states near 365 nm that generate subwavelength interference fringes with a period of 120 nm, corresponding to approximately λ/3. Enhanced field localization in the photoresist produces peak intensities of ~600× the incident intensity while maintaining fringe visibility of ~0.999. The resonances remain robust for practical incidence-angle and grating-photoresist spacing variations, including a 1-µm separation compatible with conventional lithographic processing. The large resonant enhancement can reduce exposure times by nearly three orders of magnitude or equivalently lower required laser power. These results establish guided-mode-resonance field transfer as a potential route toward high-resolution, low-power evanescent-wave interference lithography using all-dielectric structures.

