Related Experiment Video
Updated: Feb 1, 2026

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities
Published on: May 24, 2022
Endodontic sealers based on calcium silicates: a systematic review.
David Donnermeyer1, Sebastian Bürklein2, Till Dammaschke1
1Department of Periodontology and Operative Dentistry, Westphalian Wilhelms-University, Albert-Schweitzer-Campus 1, Building W 30, 48149, Münster, Germany.
New calcium silicate-based endodontic sealers offer enhanced bioactivity and healing properties beyond just sealing. Further clinical studies are needed to balance their bioactivity with potential solubility concerns for optimal root canal obturation.
Area of Science:
- Biomaterials Science
- Endodontics
- Dental Materials
Background:
- Calcium silicate-based sealers represent a novel class of endodontic materials.
- These sealers aim to improve root canal obturation by incorporating antibacterial and bioactive properties.
- Current sealers focus on achieving a bacteria-tight seal, but new materials offer enhanced healing and hard tissue formation.
Purpose of the Study:
- To review the characteristics and potential of calcium silicate-based endodontic sealers.
- To highlight the shift towards bioactive materials in root canal obturation.
- To identify the need for further clinical research on the efficacy and limitations of these sealers.
Main Methods:
- Review of existing literature on calcium silicate-based endodontic sealers.
- Analysis of the composition, setting reactions, and properties of one-component and two-component sealers.
- Discussion of in vitro characteristics and the implications of sealer bioactivity and solubility.
Main Results:
- Calcium silicate-based sealers undergo hydration and calcium phosphate precipitation reactions.
- Variations in sealer composition lead to differences in physical, chemical, and in vitro properties.
- The bioactive potential is linked to slight solubility, which may also affect sealing quality.
Conclusions:
- Calcium silicate-based sealers offer promising advancements in endodontic treatment beyond traditional sealing.
- The balance between bioactivity and solubility requires further investigation for clinical application.
- More clinical studies are essential to determine the long-term relevance and effectiveness of these materials.
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Random and Systematic Errors
Systematic Sampling Method
Systematic sampling is one of the simplest methods...
Propagation of Uncertainty from Systematic Error
Systematic Error: Methodological and Sampling Errors
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...

