Related Experiment Video
Updated: Feb 1, 2026

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
Published on: November 15, 2024
How to Publish Rigorous Experiments in the 21st Century
1Princeton University.
Abstract:
Crises provide an opportunity for the field to take stock, as do the articles in this special issue. Constructive advice for 21st century publication standards includes appropriate theory, internal validity, and external validity. First, well-grounded theory can produce a priori plausibility, testable logic, and a focus on the ideas involved, all cumulatively informed by meta-analysis across studies. Second, internal validity benefits from both exploratory work and confirmatory analyses on well-powered samples that require systematic detection and principled decisions about data quality. Inferences benefit from manipulated mediation analysis and from careful interpretation without over-claiming. Finally, external validity profits from a variety of exact and conceptual replications, best evaluated by meta-analysis.
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