Related Experiment Video
Updated: Feb 1, 2026

Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Successful percutaneous retrieval of a micra transcatheter pacing system at 8 weeks after implantation
Masatsugu Nozoe1, Daisuke Yoshida1, Daisuke Nagatomo1
1Division of Cardiology, Cardiovascular and Aortic Center Saiseikai Fukuoka General Hospital Fukuoka Japan.
Abstract:
An 86-year-old woman suffering from repeated methicillin-resistant Staphylococcus aureus (MRSA) bacteremia underwent percutaneous lead extraction using an excimer laser. Since negative blood cultures were confirmed three times after lead extraction under intravenous infusion of anti-MRSA drugs, a Micra transcatheter pacing system (Micra TPS) was implanted 7 days after the lead extraction. Although infusion of anti-MRSA drugs was continued for 5 weeks, MRSA was isolated in four separate samples of blood cultures 3 weeks after the discontinuation of the anti-MRSA therapy. The micra TPS was successfully retrieved using a steerable sheath and snare at 8 weeks after implantation.
Insights
A patient with recurrent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia experienced a relapse after Micra transcatheter pacing system (TPS) implantation. The Micra TPS was successfully retrieved, highlighting challenges in managing MRSA infections with novel pacing devices.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Device Technology
Background:
- Recurrent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia poses significant clinical challenges, particularly in patients requiring cardiac pacing.
- Percutaneous lead extraction using excimer laser is a viable option for managing infected pacing leads.
Observation:
- Following successful MRSA lead extraction and a period of negative blood cultures, a Micra transcatheter pacing system (TPS) was implanted.
- Despite continued anti-MRSA drug therapy, the patient experienced a relapse of MRSA bacteremia three weeks after therapy cessation.
- The Micra TPS was successfully retrieved using a steerable sheath and snare eight weeks post-implantation.
Findings:
- The study demonstrates a case of MRSA bacteremia recurrence after Micra TPS implantation in a patient with a history of persistent MRSA infection.
- Successful retrieval of the Micra TPS was achieved, indicating the feasibility of device removal in the context of recurrent infection.
Implications:
- This case highlights the potential risks and management complexities of transcatheter pacing systems in patients with a history of recurrent MRSA bacteremia.
- Further research is warranted to establish optimal strategies for managing patients with device-associated MRSA infections and to evaluate the long-term outcomes of alternative pacing solutions.
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