Related Experiment Video
Updated: Jan 31, 2026
07:16
Extraction of the EPP Component from the Surface EMG
Published on: December 16, 2009
12.9K
Reversible spontaneous EMG activity during myasthenic crisis: Two case reports.
Theocharis Tsironis1,2, Santiago Catania1
1Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Eneurologicalsci
|December 18, 2018
Summary
Severe Myasthenia Gravis (MG) can present with spontaneous EMG activity, mimicking other neuromuscular disorders. This case highlights the importance of considering MG even with atypical EMG findings to ensure timely diagnosis and treatment.
Area of Science:
- Neurology
- Neurophysiology
- Autoimmune Disorders
Background:
- Myasthenia Gravis (MG) is an autoimmune neuromuscular disorder characterized by fatigable muscle weakness.
- Standard EMG findings in MG typically include decremental response and increased jitter, with spontaneous activity considered atypical.
Observation:
- Two patients with severe bulbar symptoms presented with spontaneous EMG activity.
- Initial diagnoses were inflammatory myopathy and anterior horn cell disease due to these atypical EMG findings.
Findings:
- Despite atypical EMG findings, subsequent investigations including anti-AchR antibody testing and response to treatment confirmed Myasthenia Gravis.
- This indicates that spontaneous EMG activity can occur in severe MG cases.
Implications:
- Clinically severe Myasthenia Gravis may exhibit spontaneous EMG activity, potentially mimicking other neurological conditions.
- Recognizing this atypical presentation is crucial to avoid diagnostic delays and ensure appropriate management of MG.
Related Concept Videos
02:21Spontaneity
29.8K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
29.8K
01:24Data Reporting and Recording
5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
01:30Spontaneous and Induced Mutations
2.3K
Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).
2.3K
01:25Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
01:14Reversible and Irreversible Processes
5.8K
The thermodynamic processes can be classified into reversible and irreversible processes. The processes that can be restored to their initial state are called reversible processes. It is only possible if the process is in quasi-static equilibrium, i.e., it takes place in infinitesimally small steps, and the system remains at equilibrium However, these are ideal processes and do not occur naturally. An ideal system undergoing a reversible process is always in thermodynamic equilibrium within...
5.8K
01:14Diode: Reverse bias
1.9K
A diode is reverse-biased when the positive terminal of an external voltage source is connected to the n-type material and the negative terminal to the p-type material. This configuration opposes the natural direction of current flow through the diode, effectively increasing the width of the depletion region and the barrier potential. The reverse bias condition produces a minimal leakage current, primarily due to minority charge carriers. This leakage becomes significant when the reverse...
1.9K