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Related Experiment Video

Updated: Jan 31, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
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Effects of Binge Drinking on the Developing Brain: Studies in Humans.

Scott A Jones1, Jordan M Lueras1, Bonnie J Nagel1

  • 1Scott A. Jones and Jordan M. Lueras are graduate students in the Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon. Bonnie J. Nagel, Ph.D., is an associate professor in the Departments of Behavioral Neuroscience and Psychiatry, Oregon Health & Science University, Portland, Oregon.

Alcohol Research : Current Reviews
|December 18, 2018
PubMed
Summary
This summary is machine-generated.

Binge drinking and heavy alcohol use in young people can cause brain changes and increase the risk of alcohol use disorder (AUD) later in life. This review explores recent neuroimaging findings in adolescents and young adults.

Keywords:
Alcohol misusebinge drinkingcollege drinkingneurodevelopmentneuroimagingyoung adults

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Area of Science:

  • Neuroscience
  • Addiction Research
  • Developmental Psychology

Background:

  • Binge drinking is common alcohol misuse in adolescents and young adults.
  • It involves consuming 4-5+ alcoholic drinks in ~2 hours, raising blood alcohol concentration to .08% or higher.
  • Heavy drinking is defined by frequency (5+ days/month) and meets the same BAC criteria.

Purpose of the Study:

  • To review recent neuroimaging findings in adolescents and young adults who engage in binge or heavy drinking.
  • To understand the neurobiological changes associated with these drinking patterns during a critical developmental period.

Main Methods:

  • Review of recent neuroimaging studies.
  • Focus on adolescents and young adults.
  • Examination of binge drinking and heavy drinking patterns.

Main Results:

  • Binge and heavy drinking are linked to neurobiological changes in young people.
  • These patterns increase the risk of developing an alcohol use disorder (AUD) later in life.
  • Significant neuromaturation occurs during adolescence and young adulthood, making this period vulnerable.

Conclusions:

  • Binge and heavy drinking in youth are associated with neurobiological alterations.
  • These drinking patterns elevate the risk for future alcohol use disorder.
  • Understanding these neurobiological changes is crucial for prevention and intervention efforts.