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Developmental Trajectories and Reference Percentiles for the 6-Minute Walk Test for Children With Cerebral Palsy
Alyssa LaForme Fiss1, Lynn Jeffries, Kristie Bjornson
1Department of Physical Therapy (Dr Fiss), Mercer University, Atlanta, Georgia; Department of Rehabilitation Science (Dr Jeffries), University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Developmental Medicine (Dr Bjornson), Seattle Children's Hospital, Seattle, Washington; Avery Information Services Ltd (Ms Avery), Orillia, Ontario, Canada; Department of Health Research Methods, Evidence, and Impact (Dr Hanna), McMaster University, Hamilton, Ontario, Canada; Rehabilitation Medicine (Dr McCoy), University of Washington, Seattle, Washington.
Insights
This study tracked the 6-minute walk test (6MWT) in children with cerebral palsy, developing reference percentiles to aid intervention planning for improved walking capacity.
Area of Science:
- Pediatric rehabilitation
- Neurology
- Biomedical engineering
Background:
- Cerebral palsy (CP) significantly impacts motor function, affecting walking capacity.
- The 6-minute walk test (6MWT) is a key measure of functional mobility in children.
- Understanding developmental trajectories is crucial for effective intervention.
Purpose of the Study:
- To document longitudinal developmental trajectories of 6-minute walk test (6MWT) distances in children with cerebral palsy (CP).
- To develop age-specific reference percentiles for the 6MWT across different Gross Motor Function Classification System (GMFCS) levels (I-III).
Main Methods:
- A cohort of 456 children with CP, aged 3-12 years and GMFCS levels I-III, participated.
- Children's motor function was classified using the GMFCS.
- The 6MWT was administered 2-5 times over a 2-year period to capture longitudinal data.
Main Results:
- Longitudinal data revealed that 6MWT distances increase with age, with a subsequent tapering as children approach their functional limits.
- These changes are relative to their specific GMFCS level.
- Reference percentile graphs were generated to facilitate monitoring of changes over time.
Conclusions:
- The established 6MWT longitudinal developmental trajectories and reference percentiles provide valuable tools for assessing functional walking capacity.
- Interpretation of percentile changes can guide collaborative and proactive intervention planning for children with CP.
- This research supports evidence-based strategies to enhance mobility and functional outcomes in pediatric CP.
Purpose:
The purposes of this study were to document longitudinal developmental trajectories in 6-minute walk test (6MWT) distances and to develop age-specific reference percentiles for children across different Gross Motor Function Classification System (GMFCS) levels.
Methods:
A TOTAL OF: 456 children with cerebral palsy ages 3 to 12 years of, GMFCS levels I to III participated. Children's motor function was classified on the GMFCS, and children completed the 6MWT 2 to 5 times in 2 years.
Results:
Longitudinal developmental trajectories support that 6MWT distances increase with age followed by a tapering, as children approach their functional limit relative to their GMFCS level. Reference percentile graphs were created to monitor change over time.
Conclusions:
The 6MWT longitudinal developmental trajectories, reference percentiles, and interpretation of percentile change should assist collaborative and proactive intervention planning relative to functional walking capacity for children with cerebral palsy.
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