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Updated: Jan 31, 2026
07:33
Noninvasive, High-throughput Determination of Sleep Duration in Rodents
Published on: April 18, 2018
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Sleep Duration and Proteinuria Progression: A Population-Based Cohort Study.
Yi-Cheng Chang1,2,3,4, Chia-Hsuin Chang1,2,5, Yi-Ting Huang5
1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
American Journal of Nephrology
|December 18, 2018
Summary
Short sleep duration is linked to increased risk of proteinuria progression. This study highlights the importance of adequate sleep for kidney health, even after accounting for various risk factors.
Area of Science:
- Nephrology
- Sleep Medicine
- Public Health
Background:
- Sleep is a known factor in cardiovascular and metabolic health.
- The specific impact of sleep duration on kidney function is not well understood.
Purpose of the Study:
- To investigate the association between sleep duration and kidney function, specifically proteinuria and estimated glomerular filtration rate (eGFR).
Main Methods:
- A cohort of 26,249 adults in Taiwan underwent health examinations.
- Sleep duration was self-reported, and proteinuria was assessed via urine dipstick tests.
- Statistical analyses examined the relationship between sleep duration and proteinuria/eGFR over a 2.62-year follow-up.
Main Results:
- Short sleep duration (<6 hours) was associated with a higher risk of proteinuria progression.
- Even after adjusting for multiple confounding factors, short sleep remained a significant predictor.
- No significant differences in eGFR were observed across different sleep duration groups.
Conclusions:
- Short sleep duration is an independent risk factor for the progression of proteinuria.
- Maintaining adequate sleep may be crucial for preserving kidney health and preventing proteinuria development.
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