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Updated: Jan 31, 2026

Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing
Published on: September 15, 2023
Potential clinical applications of circulating cell-free DNA in ovarian cancer patients
Ana Barbosa1, Ana Peixoto2, Pedro Pinto1
1Cancer Genetics Group,IPO-Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO-Porto),Porto,Portugal.
Abstract:
Circulating cell-free DNA (cfDNA) consists of small fragments of DNA that circulate freely in the bloodstream. In cancer patients, a fraction of cfDNA is derived from tumour cells, therefore containing the same genetic and epigenetic alterations, and is termed circulating cell-free tumour DNA. The potential use of cfDNA, the so-called 'liquid biopsy', as a non-invasive cancer biomarker has recently received a lot of attention. The present review will focus on studies concerning the potential clinical applications of cfDNA in ovarian cancer patients.
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