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The Prevalence of Risk Factors for the Development of Bacteraemia in Children

Sayed Yousef Mojtahedi1, Aliakbar Rahbarimanesh2, Leila Khedmat3

  • 1Department of Pediatric Nephrology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Open Access Macedonian Journal of Medical Sciences
|December 19, 2018
PubMed

Insights

This study identified key risk factors for bacteremia in children, finding Enterobacter species as the most common pathogen. These findings highlight the need for targeted interventions in pediatric sepsis management.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Public Health

Background:

  • Bacteremia in children poses a significant public health challenge, with severe sepsis exhibiting high morbidity and mortality rates comparable to adults.
  • Understanding the prevalence of risk factors is crucial for effective prevention and treatment strategies in pediatric populations.

Purpose of the Study:

  • To determine the frequency of risk factors associated with bacteremia in children under 15 years of age.
  • To identify common causative microorganisms in pediatric bacteremia cases.

Main Methods:

  • A retrospective study was conducted on 84 children hospitalized in Bahrami Hospital between 2013 and 2016.
  • Data collected included patient demographics, hospitalization details, blood transfusion history, and blood culture results.

Main Results:

  • Blood cultures were positive in 35.7% of cases, with Enterobacter (81.48%) being the predominant pathogen, followed by Escherichia coli and Klebsiella.
  • Commonly observed risk factors included hospitalization in internal wards (50%) and a history of blood transfusion (11.2%).
  • The average duration of hospitalization was 15.30 ± 8.75 days.

Conclusions:

  • Pediatric severe sepsis is a significant public health concern requiring further investigation.
  • International clinical trials are needed to develop and evaluate targeted interventions for children with severe sepsis.
Abstract

Keywords:
ChildrenRisk factorSeptic shockSepticemiaSystemic inflammatory response Syndrome

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