Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Valves01:16

Heart Valves

12.1K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
12.1K
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

520
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
520
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

574
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
574
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

371
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
371
Migration00:53

Migration

8.9K
Migration is long-range, seasonal movement from one region or habitat to another. This common strategy, carried out by many different organisms around the world, is an adaptive response that typically corresponds to changes in an organism’s environment, like resource availability or climate. Migrations can involve huge groups of thousands of animals as well as single individuals traveling alone and can range from thousands of kilometers to just a few hundred meters.
8.9K
Fixing Double-strand Breaks02:04

Fixing Double-strand Breaks

14.7K
The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
14.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Tips and tricks" for optimizing the role of gravity force during colonic endoscopic submucosal dissection: a single center experience.

Minerva surgeryยท2026
Same author

Have mediators and at-risk time shaped the Lipoprotein(a)-dementia null? Author's reply.

European journal of internal medicineยท2026
Same author

Transarterial embolization in the management of chronic shoulder pain: clinical evidence and emerging therapeutic role.

Frontiers in radiologyยท2026
Same author

Breaking barriers in stroke care: the role of peripheral interventional radiologists in mechanical thrombectomy.

La Radiologia medicaยท2026
Same author

Diabetes, impaired fasting glucose, and cognitive trajectories: a multi-cohort study.

medRxiv : the preprint server for health sciencesยท2026
Same author

Impact of anxiety and depression in patients with atrial fibrillation: Insights from 2 international prospective registries.

Heart rhythmยท2026

Related Experiment Video

Updated: Jan 31, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.7K

Double Valve Failure Due to Perceval Sutureless Aortic Valve Migration.

Michele Rossi1, Lucia Cristodoro2, Devotini Roger2

  • 1Cardiac Surgery Unit, Heart Center, Grande Ospedale Metropolitano 'Bianchi-Melacrino-Morelli', Reggio Calabria, Italy. Electronic correspondence: michele.r@libero.i.

The Journal of Heart Valve Disease
|December 19, 2018
PubMed
Summary

A rare case of Perceval sutureless aortic valve migration caused severe heart valve insufficiency. Prompt valve replacement restored normal heart function, emphasizing careful patient monitoring post-implantation.

More Related Videos

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
05:47

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro

Published on: May 10, 2021

4.7K
Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
07:12

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves

Published on: August 23, 2011

16.3K

Related Experiment Videos

Last Updated: Jan 31, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.7K
Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
05:47

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro

Published on: May 10, 2021

4.7K
Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
07:12

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves

Published on: August 23, 2011

16.3K

Area of Science:

  • Cardiovascular Surgery
  • Medical Device Technology
  • Cardiac Imaging

Background:

  • Sutureless aortic valves offer minimally invasive options for aortic valve replacement.
  • Early complications, though rare, require thorough investigation and management.

Observation:

  • A 76-year-old woman presented with pulmonary edema five months post-Perceval sutureless aortic valve implantation.
  • Imaging revealed the aortic valve had migrated into the left ventricle.

Findings:

  • The migrated valve caused severe aortic and secondary mitral insufficiency.
  • Surgical replacement with a standard bioprosthesis resolved the insufficiency and restored native mitral valve function.

Implications:

  • This case represents a novel presentation of early proximal migration of the Perceval valve.
  • Highlights the critical need for meticulous preoperative evaluation and diligent postoperative surveillance following sutureless aortic valve implantation.