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Updated: Jan 31, 2026

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
[Neurofibromatosis type 1 and attention-deficit disorder. Our current experience]
S B Sanchez-Marco1, J Lopez-Pison1, I Serrano-Vinuales1
1HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in neurofibromatosis type 1 (NF1) patients. Early diagnosis and treatment show good adherence and positive outcomes in this population.
Area of Science:
- Pediatric Neurology
- Genetics
- Neurodevelopmental Disorders
Background:
- Neurofibromatosis type 1 (NF1) is associated with a significant predisposition to attention-deficit disorders.
- Understanding the prevalence of attention-deficit/hyperactivity disorder (ADHD) in NF1 patients is crucial for timely intervention.
Purpose of the Study:
- To determine the prevalence of ADHD diagnosis in pediatric patients with NF1.
- To assess patient adherence and medical treatment outcomes for ADHD in NF1.
- To highlight the importance of early diagnosis and treatment for ADHD in NF1.
Main Methods:
- Retrospective identification of NF1 patients diagnosed with ADHD.
- Data collection included clinical information and treatment details.
- Study period: December 31, 2015, to June 31, 2017.
Main Results:
- 23 out of 56 (41%) enrolled NF1 patients were diagnosed with ADHD.
- The mean age at ADHD diagnosis was 7.53 ± 2.46 years.
- 86% of patients receiving treatment continued, with moderate to positive reported effects.
Conclusions:
- The prevalence of ADHD in NF1 patients is notably high.
- Early ADHD diagnosis and treatment in NF1 patients are essential.
- Most NF1 patients exhibit good adherence and positive outcomes with medical treatment for ADHD.
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