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In vivo Evaluation of Mucociliary Clearance in Mice
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Investigation modalities for evaluation of esophageal clearance function
Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 19, 2018
Summary
Esophageal clearance transports food via peristalsis, evaluated using manometry and barium swallow. These methods assess esophageal motility and transient lower esophageal sphincter relaxation in reflux esophagitis.
Area of Science:
- Gastroenterology
- Physiology
Background:
- Esophageal clearance is crucial for transporting food from the pharynx to the stomach.
- This process relies on peristaltic waves, initiated by swallowing.
Purpose of the Study:
- To outline the investigation modalities for evaluating esophageal clearance function.
- To highlight the role of esophageal motility and transient lower esophageal sphincter relaxation (TLESR) assessment in reflux esophagitis.
Main Methods:
- Esophageal manometry (including high-resolution manometry)
- Esophageal radiography (barium swallow)
- Esophageal scintigraphy
- Ultrasonography
- Impedance methods
- Combination with transnasal endoscopy and manometry
Main Results:
- Various investigation modalities can assess esophageal clearance.
- Quantitative assessment of esophageal motility is a key component.
- Transient lower esophageal sphincter relaxation (TLESR) is evaluated in the context of reflux esophagitis.
Conclusions:
- Multiple diagnostic tools are available for esophageal clearance evaluation.
- Manometry and barium swallow are key methods for assessing esophageal motility.
- Understanding esophageal clearance is vital for managing conditions like reflux esophagitis.
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