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Updated: Jan 31, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
Personalized peptide vaccine for cancer treatment; now and its future
Abstract:
Therapeutic cancer vaccines have been dramatically progressing in a variety of their forms for the last two decades. The CTIepitope peptide vaccines are one of them. We proposed the personalized peptide vaccine (PPV) therapy. Our PPV is different from the classical one in that a maximum of four peptides are selected based on the patient's HLA-A types and.their pre-existing immunity (=immunological memory), leading to the more rapid and stronger re- sponses to the vaccinated peptides. Since then, we have been conducting clinical studies for various types of advanced cancers. We summarized the clinical outcomes of the PPV studies and described its prospect for the clinical application.
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