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Updated: Jan 31, 2026
13:14
Genetic Barcoding with Fluorescent Proteins for Multiplexed Applications
Published on: April 14, 2015
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Barcoded point-of-care bioassays
Mingzhu Yang1, Yong Liu, Xingyu Jiang
1Beijing Engineering Research Center for BioNanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for NanoScience and Technology, No. 11 Zhongguancun Beiyitiao, Beijing, 100190, P. R. China. xingyujiang@nanoctr.cn.
Chemical Society Reviews
|December 20, 2018
Summary
Barcode technology offers advanced biomarker identification for healthcare. This review highlights barcode encoding and decoding for point-of-care testing (POCT), emphasizing future directions and challenges.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Diagnostics
Background:
- Barcode technology offers a promising avenue for multiplexed biomarker detection in healthcare.
- Current barcode applications in bioassays require advancements for point-of-care testing (POCT) suitability.
- While barcode encoding is advanced, decoding strategies for simplified POCT remain underexplored.
Purpose of the Study:
- To provide a comprehensive review of barcode encoding and decoding technologies.
- To emphasize the potential of barcoded bioassays in point-of-care testing (POCT).
- To discuss future directions and challenges for barcoded bioassays in POCT.
Main Methods:
- Review of existing literature on barcode encoding and decoding in bioassays.
- Analysis of advancements in manufacturing and portable devices for barcoded bioassays.
- Exploration of simplified decoding strategies for POCT applications.
Main Results:
- Barcode technology enables sensitive and specific biomarker identification and signal amplification.
- Emerging portable cartridges and miniaturized devices facilitate the integration of barcoded bioassays with POCT.
- Significant progress in barcode library fabrication has been achieved.
Conclusions:
- Barcode technology holds substantial potential for transforming biomarker identification and signal amplification in clinical examinations.
- The integration of barcoded bioassays with portable devices presents a viable pathway for robust and user-friendly POCT.
- Further development in decoding technologies is crucial for the widespread adoption of barcoded bioassays in POCT settings.
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