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Miliary Lung Metastases from Genital Large Cell Neuroendocrine Carcinomas
Akimasa Sekine1, Makiko Satoh2,3, Koji Okudela4
1Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Abstract:
We herein report two cases of miliary lung metastases from genital carcinoma in uterine cervix and endometrium. Notably, these patients were unable to receive any anti-tumor chemotherapy due to rapid progression causing respiratory failure, and they ultimately died of disease progression within only a month after the first visit to our hospitals. A postmortem examination confirmed the diagnosis of genital large-cell neuroendocrine carcinoma (LCNEC). Chest physicians should be aware of genital LCNEC with a dismal prognostic entity as an important differential diagnosis of miliary lung metastases.
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