Scarlet fever associated with hepatitis in pediatrics. A case report

Arvind V Panchoo1, Miguel Saps2, Edgardo D Rivera Rivera2

  • 1Department of Pediatrics, Jackson Memorial Hospital, USA.

Insights

Scarlet fever can rarely cause hepatitis in children, presenting with jaundice and elevated liver enzymes. This complication is typically benign, with full recovery expected within weeks to months.

Area of Science:

  • Pediatric Infectious Diseases
  • Hepatology
  • Microbiology

Background:

  • Scarlet fever, caused by group A beta-hemolytic Streptococcus (GABHS), is a common pediatric illness.
  • Hepatitis is a rare complication of scarlet fever, observed more frequently in adults than children.
  • This case report details a pediatric patient experiencing hepatitis secondary to scarlet fever.

Observation:

  • A 12-year-old male presented with jaundice, dark urine, and anorexia following a scarlet fever diagnosis.
  • Laboratory results showed elevated liver enzymes and bilirubin levels.
  • Extensive testing excluded common viral hepatitis and other infectious causes of hepatitis.

Findings:

  • The patient's presentation and laboratory findings were consistent with hepatitis.
  • No other identifiable cause for hepatitis was found, suggesting a link to scarlet fever.
  • Abdominal ultrasound revealed no abnormalities.

Implications:

  • This case highlights hepatitis as a rare, yet possible, complication of scarlet fever in pediatric patients.
  • The exact pathogenesis remains unclear, but streptococcal pyrogenic exotoxins are implicated.
  • Complete recovery is anticipated, underscoring the generally benign nature of this complication.
Abstract

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