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Porcine Model of Infrarenal Abdominal Aortic Aneurysm
Published on: November 21, 2019
Coronary Artery Disease as a Relevant Risk Factor in Screening of Abdominal Aortic Ectasia and Aneurysm
Ahmed Koshty1, Magdalena Bork2,3, Andreas Böning4
1Department of Vascular Surgery, Evangelisches Jung Stilling Krankenhaus GmbH, Siegen, Nordrhein-Westfalen, Germany.
Insights
The prevalence of abdominal aortic aneurysm (AAA) is high in coronary artery disease (CAD) patients. Elderly patients with three-vessel CAD should be considered for AAA screening programs.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Epidemiology
Background:
- Coronary artery disease (CAD) is a significant health concern.
- Abdominal aortic aneurysm (AAA) and abdominal aortic ectasia (AAE) are serious vascular conditions.
- The prevalence of AAA/AAE in CAD patients requires further investigation.
Purpose of the Study:
- To determine the prevalence of AAA and AAE in patients with CAD.
- To identify factors associated with AAA occurrence in this population.
- To gather data for establishing AAA screening programs for CAD patients.
Main Methods:
- A multicenter study involving 500 patients with suspected or diagnosed CAD.
- Sonographic examination of the infrarenal abdominal aorta was performed.
- Prevalence of AAA and AAE was calculated, and associated factors were analyzed.
Main Results:
- Overall prevalence of AAE was 35.1% and AAA was 5.4% in CAD patients.
- In patients with three-vessel CAD, AAE prevalence was 34% and AAA was 6.8%.
- Significant correlations were found between three-vessel CAD and AAA, and AAA and age >65 years.
Conclusions:
- The prevalence of AAA in CAD patients is notably high.
- Elderly patients with three-vessel CAD are particularly at risk.
- Inclusion of CAD patients, especially elderly with three-vessel CAD, in AAA screening programs is recommended.
Background:
The aim of this study was to investigate the prevalence of abdominal aortic aneurysm (AAA) and abdominal aortic ectasia (AAE) in coronary artery disease (CAD) patients in a multicenter setting to obtain significant data to establish an AAA screening program in our departments.
Methods:
Between January and September 2016, 500 patients with suspected or diagnosed CAD planned for coronary angiography or coronary artery bypass graft (CABG) underwent a sonographic examination of the infrarenal abdominal aorta to diagnose AAA or AAE. We calculated the prevalence of AAA and AAE in patients diagnosed of CAD and investigated factors potentially associated with the occurrence of AAA.
Results:
The overall prevalence in all grades of CAD for AAE was 35.1% and for AAA 5.4%. In patients with three-vessel CAD, the prevalence of AAE was 34% and of AAA 6.8%. Significant correlation was found between the three-vessel CAD and AAA (p = 0.039). The logistic regression analysis showed significant correlation between AAA and age > 65 years (p = 0.05). The multivariate analysis of risk factors and CAD revealed significant correlations between one-vessel CAD and arterial hypertension (AH) (p = 0.004) and age > 65 years (p = 0.001) as well as between three-vessel CAD and AH (p = 0.01), peripheral artery disease (p = 0.01), and age > 65 years (p = 0.03).
Conclusion:
Our results confirm, that in comparison to other data, the prevalence of AAA in patients with CAD is high. Thus, it is recommended to include patients with CAD, especially elderly patients with three-vessel CAD, in future AAA screening programs.
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