Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
What are Estimates?01:06

What are Estimates?

8.8K
It isn't easy to measure a parameter such as the mean height or the mean weight of a population. So, we draw samples from the population and calculate the mean height or mean weight of the individuals in the sample. This sample data acts as a representative measure of the population parameter. These sample statistics are known as estimates. 
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
8.8K
Network Covalent Solids02:18

Network Covalent Solids

16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
Estimation of k and VD of Aminoglycosides01:20

Estimation of k and VD of Aminoglycosides

242
Aminoglycosides are a class of antibiotics used to treat various bacterial infections. Clinicians must determine the elimination rate constant (k) and volume of distribution (VD) to optimize therapeutic efficacy and minimize toxicity. The k value represents the rate at which the drug is removed from the body, and the VD reflects the degree to which the drug distributes into body tissues. Accurately estimating these parameters allows healthcare professionals to tailor drug dosing to individual...
242
Fast Fourier Transform01:10

Fast Fourier Transform

943
The Fast Fourier Transform (FFT) is a computational algorithm designed to compute the Discrete Fourier Transform (DFT) efficiently. By breaking down the calculations into smaller, manageable sections, the FFT significantly reduces the computational complexity involved. Direct computation of an N-point DFT requires N2 complex multiplications, whereas the FFT algorithm needs only (N/2)log⁡2N multiplications, offering a much faster performance.
The computational efficiency of the FFT becomes...
943
Neural Regulation01:37

Neural Regulation

43.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncovering Sex Differences in the Drosophila Ventral Nerve Cord Through Connectome Alignment.

bioRxiv : the preprint server for biology·2026
Same author

Author Correction: Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life.

Nature neuroscience·2026
Same author

Precise calcium-to-spike inference using biophysical generative models.

bioRxiv : the preprint server for biology·2026
Same author

Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life.

Nature neuroscience·2026
Same author

Distributed control circuits across a brain-and-cord connectome.

Nature·2026
Same author

High-frequency spike inference with particle Gibbs sampling.

eLife·2026
Same journal

RNAbpFlow: base pair-augmented SE(3) flow matching for conditional RNA 3D structure generation.

Nature methods·2026
Same journal

Spatio-DARLIN enables robust and efficient in situ lineage tracing in mice at single-cell resolution.

Nature methods·2026
Same journal

EasyGrid: a versatile platform for automated cryo-EM sample preparation and quality control.

Nature methods·2026
Same journal

Cloud-based microscope enables live neuroimaging for 24 h and beyond with worldwide access.

Nature methods·2026
Same journal

Deep molecular profiling in three dimensions.

Nature methods·2026
Same journal

3D pathology-guided microdissection.

Nature methods·2026
See all related articles

Related Experiment Video

Updated: Jan 31, 2026

Deep Neural Networks for Image-Based Dietary Assessment
13:19

Deep Neural Networks for Image-Based Dietary Assessment

Published on: March 13, 2021

10.0K

Fast animal pose estimation using deep neural networks.

Talmo D Pereira1, Diego E Aldarondo1,2, Lindsay Willmore1

  • 1Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.

Nature Methods
|December 22, 2018
PubMed
Summary
This summary is machine-generated.

LEAP estimates animal pose (LEAP) is a deep learning tool that accurately tracks animal body parts in videos. This automated system enhances behavioral analysis for fruit flies and mice with high precision.

More Related Videos

Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
03:31

Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

Published on: December 15, 2023

1.1K
Integration of Animal Behavioral Assessment and Convolutional Neural Network to Study Wasabi-Alcohol Taste-Smell Interaction
06:19

Integration of Animal Behavioral Assessment and Convolutional Neural Network to Study Wasabi-Alcohol Taste-Smell Interaction

Published on: August 16, 2024

874

Related Experiment Videos

Last Updated: Jan 31, 2026

Deep Neural Networks for Image-Based Dietary Assessment
13:19

Deep Neural Networks for Image-Based Dietary Assessment

Published on: March 13, 2021

10.0K
Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
03:31

Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

Published on: December 15, 2023

1.1K
Integration of Animal Behavioral Assessment and Convolutional Neural Network to Study Wasabi-Alcohol Taste-Smell Interaction
06:19

Integration of Animal Behavioral Assessment and Convolutional Neural Network to Study Wasabi-Alcohol Taste-Smell Interaction

Published on: August 16, 2024

874

Area of Science:

  • Computational Biology
  • Ethology
  • Machine Learning

Background:

  • Automated animal pose tracking is crucial for complex behavioral analyses.
  • Existing methods may lack efficiency or accuracy for detailed pose estimation.

Purpose of the Study:

  • Introduce LEAP (LEAP estimates animal pose), a deep-learning framework for precise animal pose tracking.
  • Validate LEAP's performance across different species and imaging conditions.

Main Methods:

  • Developed a deep-learning model for predicting animal body part positions.
  • Integrated a graphical interface for user-friendly labeling and network training.
  • Validated using videos of fruit flies and mice, tracking up to 32 body points.

Main Results:

  • Achieved high accuracy with an error rate of <3% of body length in fruit flies.
  • Demonstrated rapid training, reaching 95% peak performance with only 100 frames.
  • Successfully recapitulated insect gait dynamics and enabled unsupervised behavioral classification.
  • Extended applicability to challenging imaging scenarios and freely moving mice.

Conclusions:

  • LEAP provides an efficient and accurate solution for automated animal pose estimation.
  • The framework is versatile, applicable to diverse species and research questions in behavioral biology.
  • LEAP facilitates advanced behavioral analyses and opens new avenues for scientific discovery.