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Auditory brainstem response in infants with iron deficiency anemia
Hemawathiy Sundagumaran1, Jayashree Seethapathy2
1Speech Language Pathologist & Audiologist, India.
International Journal of Pediatric Otorhinolaryngology
|December 23, 2018
Summary
Iron deficiency anemia (IDA) in infants prolongs auditory brainstem response (ABR) latencies, affecting central auditory system development. Untreated IDA can lead to lasting neuro-functional alterations.
Area of Science:
- Pediatric audiology
- Neurodevelopmental disorders
- Hematology
Background:
- Auditory brainstem response (ABR) in infants with Iron Deficiency Anemia (IDA) provides insights into central nervous system auditory pathways.
- IDA is a common condition in infants, potentially impacting neurological development.
Purpose of the Study:
- To analyze and compare absolute and interpeak latencies of ABR in infants with and without IDA.
- To investigate the impact of IDA on auditory pathway maturation.
Main Methods:
- ABR traces were recorded from 40 anemic and 40 non-anemic infant ears (6-24 months).
- Recordings utilized click stimuli at various intensity levels (70, 50, 30 dBnHL).
Main Results:
- Prolonged absolute latencies for ABR peaks (except peak I) were observed in infants with IDA across tested intensities.
- Peak amplitudes were similar at higher intensities but reduced significantly at 30 dBnHL in the IDA group.
- Interpeak latencies showed no significant difference at 70 dBnHL, but prolonged III-V and I-V latencies were noted at 50 and 30 dBnHL in infants with IDA.
Conclusions:
- Iron deficiency appears to affect the functional development of the infant auditory system.
- Untreated IDA may have long-lasting consequences on the central auditory system, altering neuro-functional maturation.
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