Related Experiment Video

Updated: Jan 31, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

22.6K

Prenatal Screening Markers for Down Syndrome: Sensitivity, Specificity, Positive and Negative Expected Value Method

Jasmina Durković1, Milan Ubavić2, Milica Durković3

  • 1Department of Genetics, Hospital Subotica, Subotica, Serbia.

Journal of Medical Biochemistry
|December 25, 2018
PubMed
Summary

This study evaluated prenatal screening markers for chromosomopathy. Combining pregnancy associated plasma protein-A (PAPP-A), free human chorionic gonadotropin (free-beta HCG), and nuchal translucency (NT) improves Down syndrome risk assessment.

Keywords:
Down syndromeprenatal screeningsensitivityspecificity

More Related Videos

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

7.0K
Development of a Negative Selectable Marker for Entamoeba histolytica06:05

Development of a Negative Selectable Marker for Entamoeba histolytica

Published on: December 12, 2010

12.8K

Related Concept Videos

Positive, Negative, and Zero Work00:58

Positive, Negative, and Zero Work

Work is done on an object when energy is transferred to the object. In other words, work is done when a force acts on a body that undergoes a displacement from one position to another. By definition, the work done by a force is the integral of the force with respect to the displacement along its path. Forces can vary as a function of position, and displacements can occur along various paths between two points. The magnitude of a force multiplied by the cosine of the angle that the force makes...
22.2K
Positive and Negative Feedback Loops01:18

Positive and Negative Feedback Loops

Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires  maintaining an internal dynamic equilibrium:
25.2K
Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
1.3K
Expected Value01:15

Expected Value

The expected value is known as the "long-term" average or mean. This means that over the long term of experimenting over and over, you would expect this average. The expected average is represented by the symbol μ. It is calculated as follows:
7.8K
Velocity and Position by Integral Method01:13

Velocity and Position by Integral Method

If acceleration as a function of time is known, then velocity and position functions can be derived using integral calculus. For constant acceleration, the integral equations refer to the first and second kinematic equations for velocity and position functions, respectively.
Consider an example to calculate the velocity and position from the acceleration function. A motorboat is traveling at a constant velocity of 5.0 m/s when it starts to decelerate to arrive at the dock. Its acceleration is...
7.8K
Velocity and Position by Graphical Method01:34

Velocity and Position by Graphical Method

Velocity and position can be calculated from the known function of acceleration as a function of time. The total area under the acceleration-time graph and the velocity-time graph gives the change in velocity and position, respectively. In the case of an airplane, its acceleration is tracked using the inertial navigation system. The pilot provides the input of the airplane's initial position and velocity before takeoff. The inertial navigation system then uses the acceleration data to...
10.0K