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Inflammation

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Paracrine Signaling

Paracrine Signaling

Paracrine signaling allows cells to communicate with their immediate neighbors via secretion of signaling molecules. Such a signal can only trigger a response in nearby target cells because the signal molecules degrade quickly or are inactivated if not taken up. Prominent examples of paracrine signaling include nitric oxide signaling in blood vessels, synaptic signaling of neurons, the blood clotting system, tissue repair/wound healing, and local allergic skin reactions. Nitric oxide as a...

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Related Experiment Video

Updated: Jan 31, 2026

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

Published on: December 9, 2021

Editorial: Endothelial Dysfunction During Inflammation and Alloimmunity

Olaf Penack¹, Thomas Luft²

¹Hematology, Charité Universitätsmedizin Berlin, Berlin, Germany.

Frontiers in Immunology

|December 25, 2018

Summary

No abstract available in PubMed .

Keywords:

alloimmune dysfunction endothelial inflammation transplantation

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